| tRNA traffic meets a cell-cycle checkpoint. | |
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MedLine Citation:
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PMID: 18045528 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The molecular pathways linking DNA-damage checkpoint proteins to cell-cycle progression remain largely unresolved. Findings by Ghavidel et al. (2007) reported in this issue suggest that tRNA trafficking and the transcription factor Gcn4 are key intermediates in the process by which yeast cells detect DNA damage and delay cell-cycle progression at the G1 to S phase transition. |
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Authors:
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Ted Weinert; Anita K Hopper |
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Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Cell Volume: 131 ISSN: 0092-8674 ISO Abbreviation: Cell Publication Date: 2007 Nov |
Date Detail:
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Created Date: 2007-11-29 Completed Date: 2008-01-30 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 0413066 Medline TA: Cell Country: United States |
Other Details:
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Languages: eng Pagination: 838-40 Citation Subset: IM |
Affiliation:
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Department of Molecular and Cellular Biology, University of Arizona, Life Sciences South 546, P.O. Box 210106, Tucson, AZ 85721-0106, USA. tweinert@email.arizona.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Active Transport, Cell Nucleus
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physiology Basic-Leucine Zipper Transcription Factors Cell Cycle / physiology* DNA Damage / physiology DNA-Binding Proteins / genetics, physiology Genes, cdc / physiology Models, Biological RNA, Transfer / metabolism* Saccharomyces cerevisiae / genetics*, metabolism Saccharomyces cerevisiae Proteins / genetics, physiology Transcription Factors / genetics, physiology |
| Chemical | |
Reg. No./Substance:
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0/Basic-Leucine Zipper Transcription Factors; 0/DNA-Binding Proteins; 0/GCN4 protein, S cerevisiae; 0/Saccharomyces cerevisiae Proteins; 0/Transcription Factors; 9014-25-9/RNA, Transfer |
| Comments/Corrections | |
Comment On:
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Cell. 2007 Nov 30;131(5):915-26
[PMID:
18045534
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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