Document Detail


A systematic review and meta-analysis of a brief delay in clamping the umbilical cord of preterm infants.
MedLine Citation:
PMID:  17890882     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The optimal timing of clamping the umbilical cord in preterm infants at birth is the subject of continuing debate.
OBJECTIVE: To investigate the effects of a brief delay in cord clamping on the outcome of babies born prematurely.
METHODS: A retrospective meta-analysis of randomised trials in preterm infants was conducted. Data were collected from published studies identified by a structured literature search in EMBASE, PubMed, CINAHL and the Cochrane Library. All infants born below 37 weeks gestation and enrolled into a randomised study of delayed cord clamping (30 s or more) versus immediate cord clamping (less than 20 s) after birth were included. Systematic search and analysis of the data were done according to the methodology of the Cochrane collaboration.
RESULTS: Ten studies describing a total of 454 preterm infants were identified which met the inclusion and assessment criteria. Major benefits of the intervention were higher circulating blood volume during the first 24 h of life, less need for blood transfusions (p = 0.004) and less incidence of intraventricular hemorrhage (p = 0.002).
CONCLUSIONS: The procedure of a delayed cord clamping time of at least 30 s is safe to use and does not compromise the preterm infant in the initial post-partum adaptation phase.
Authors:
Heike Rabe; Graham Reynolds; Jose Diaz-Rossello
Publication Detail:
Type:  Journal Article; Meta-Analysis; Review     Date:  2007-09-21
Journal Detail:
Title:  Neonatology     Volume:  93     ISSN:  1661-7819     ISO Abbreviation:  Neonatology     Publication Date:  2008  
Date Detail:
Created Date:  2008-02-08     Completed Date:  2008-04-11     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  101286577     Medline TA:  Neonatology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  138-44     Citation Subset:  IM    
Copyright Information:
(c) 2007 S. Karger AG, Basel
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MeSH Terms
Descriptor/Qualifier:
Blood Volume / physiology
Constriction
Delivery, Obstetric / methods*
Humans
Infant, Newborn
Infant, Premature / physiology*
Time Factors
Umbilical Cord / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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