Document Detail

A systematic review of concomitant interventions to prevent persistent perforations following the removal of long-term ventilation tubes.
MedLine Citation:
PMID:  19264366     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: To review the current evidence for the use of concomitant interventions to reduce the persistent perforation rate following the removal of long-term ventilation tubes.
TYPE OF REVIEW: A systematic review of the literature and meta-analysis of randomised controlled trials on this topic.
SEARCH STRATEGY: Medline (1952-2008), EMBASE (1974-2008) and the Cochrane Central Register of Controlled Trials. A combination of search terms were used in a search strategy derived from guidance from the Cochrane collaboration.
EVALUATION METHOD: A review of all trials by two authors with grading of the level of evidence.
RESULTS: Fifteen studies using a variety of interventions were identified.
CONCLUSION: A multi-centre randomised controlled trial is indicated to validate findings of previous studies and elucidate any optimum intervention to reduce the persistent perforation rate.
J Keir; R Clarke
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Publication Detail:
Type:  Journal Article     Date:  2009-03-04
Journal Detail:
Title:  International journal of pediatric otorhinolaryngology     Volume:  73     ISSN:  1872-8464     ISO Abbreviation:  Int. J. Pediatr. Otorhinolaryngol.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2011-04-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003603     Medline TA:  Int J Pediatr Otorhinolaryngol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  1321-4     Citation Subset:  IM    
Department of Otolaryngology, North Cheshire Hospitals NHS Trust, Lovely Lane, Warrington, WA5 1QG, UK.
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