Document Detail


A system model of the metabolic response to stress.
MedLine Citation:
PMID:  6357187     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The dynamic interactions of the body's response to stress are extremely complex and can best be understood within the context of an information flow diagram. In this paper such a model is developed from the biochemical equations of glycolysis and from relevant hormonal and behavioral relations. In response to a situation perceived as stressful, the body prepares for physical action by the secretion of many hormones. These hormones mobilize fatty acids and initiate glucose sparing within the body. In modern living, little attitudinal or situational change is normally undertaken to reduce the perception of stress, and the hormones continue to be secreted. As a result, chronically high levels of fatty acids, ketones, cholesterol, and very low-density lipoproteins are maintained and contribute, in the long run, to an increased risk of cardiovascular disease. An examination of the flow diagram elucidates the possible pathways leading from the perception of stress to the pathological consequences of the body's response.
Authors:
C Atkinson; J H Milsum
Related Documents :
17118457 - D-aspartic acid: an endogenous amino acid with an important neuroendocrine role.
9493877 - Fatty acids and brain peptides.
9138527 - Immunogold localization and quantification of cellular and subcellular abscisic acid, p...
23418167 - Lipophilic extracts from needles and defoliated twigs of pinus pumila from two differen...
3558647 - Quantitative determination by high-performance liquid chromatography of acetylsalicylic...
22024267 - Treatment of endometriosis with local acetylsalicylic acid injection: experimental stud...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Behavioral science     Volume:  28     ISSN:  0005-7940     ISO Abbreviation:  Behav Sci     Publication Date:  1983 Oct 
Date Detail:
Created Date:  1983-12-20     Completed Date:  1983-12-20     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  2984722R     Medline TA:  Behav Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  268-73     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Arousal / physiology
Blood Glucose / metabolism
Coronary Disease / blood
Energy Metabolism*
Fatty Acids, Nonesterified / blood
Glycolysis
Hormones / blood
Humans
Insulin / blood
Lipids / blood
Stress, Physiological / blood*
Systems Theory*
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Fatty Acids, Nonesterified; 0/Hormones; 0/Lipids; 11061-68-0/Insulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Changes in food intake and meal patterns following injection of D-mannoheptulose in rats.
Next Document:  Mechanism of activation of proximate mutagens in Ames' tester strains: the acetyl-CoA dependent enzy...