| A synthetic aragonite-based bioceramic: influence of process parameters on porosity and compressive strength. | |
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MedLine Citation:
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PMID: 11761171 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We investigate the influence of process parameters such as weight fraction and particle size of pore-former, and isostatic pressure, on porosity and compressive strength of non-sintered porous calcium carbonate biomaterials compacted at high pressure in uniaxial or isostatic mode. Experiment design and results analysis are performed according to a two-level 2k factorial design method (FDM). Results indicate that only the weight fraction of pore-former (wt fpf) influences significantly the porosity and the compressive strength. The porosity P, is described by a linear function of wt fpf, and the compressive strength sigma(comp), by an exponential one. For materials compacted under uniaxial pressing: P (vol%) = 33.7 + 85.4 (wt fpf) and sigma(comp) (MPa) = 28.8e(-9.2(wt fpf)) with 0.1 < or = wt fpf < or = 0.3. For materials compacted in isostatic mode: P (vol%) = 33.9 + 82.1 (wt fpf) and sigma(comp) (MPa) = 24.0e(-7.0(wt fpf)) with 0.15 < or = wt fpf < or = 0.35. The pore-former particle size has no significant influence on both properties. The increase in isostatic pressure provides slightly lower porosity and better compressive strength. For a fixed fraction of pore-former, isostatic pressing leads to a better compressive strength than uniaxial pressing. This study indicates that, for a constant amount of pore former, the size of macropores can be adjusted to reach optimal bone-ingrowth without change in compressive strength. |
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Authors:
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A Luca-Girot; P Langlois; J C Sangleboeuf; A Ouammou; T Rouxel; J Gaude |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Biomaterials Volume: 23 ISSN: 0142-9612 ISO Abbreviation: Biomaterials Publication Date: 2002 Jan |
Date Detail:
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Created Date: 2001-12-11 Completed Date: 2002-05-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8100316 Medline TA: Biomaterials Country: England |
Other Details:
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Languages: eng Pagination: 503-10 Citation Subset: IM |
Affiliation:
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Institut de Chimie de Rennes, Université de Rennes 1, UMR 6511, Cristallochimie et Biomatériaux, CS 74205, France. anita.lucas@univ-rennes1.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biocompatible Materials* Calcium Carbonate / chemistry* Ceramics* Materials Testing* |
| Chemical | |
Reg. No./Substance:
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0/Biocompatible Materials; 0/Ceramics; 471-34-1/Calcium Carbonate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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