| The synthesis of total and specific glycosaminoglycans during development of experimental liver cirrhosis. | |
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MedLine Citation:
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PMID: 908398 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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During hepatic fibrogenesis induced by long-term administration of thioacetamide, the synthesis of chondroitin 4,6-sulfate and hyaluronic acid was strongly enhanced; the formation of heparan sulfate comprising at least 70% of total liver GAG synthesis and of a keratan-sulfate-like fraction was stimulated 1.7 fold. Formation of dermatan-sulfate in liver could not be detected. |
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Authors:
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A M Gressner; H Pazen; H Greiling |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Experientia Volume: 33 ISSN: 0014-4754 ISO Abbreviation: Experientia Publication Date: 1977 Oct |
Date Detail:
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Created Date: 1977-11-30 Completed Date: 1977-11-30 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0376547 Medline TA: Experientia Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 1290-2 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Chondroitin / biosynthesis Glycosaminoglycans / biosynthesis* Heparitin Sulfate / biosynthesis Hyaluronic Acid / biosynthesis Keratan Sulfate / biosynthesis Liver / metabolism* Liver Cirrhosis, Experimental / metabolism* Male Rats Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Glycosaminoglycans; 9004-61-9/Hyaluronic Acid; 9007-27-6/Chondroitin; 9050-30-0/Heparitin Sulfate; 9056-36-4/Keratan Sulfate |
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