Document Detail


The synthesis of medium-chain fatty acids by lactating-rabbit mammary gland studied in vitro.
MedLine Citation:
PMID:  4722894     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The proportion of C(8:0) and C(10:0) fatty acids synthesized by the microsomal plus particle-free supernatant fraction from lactating rabbit mammary gland is enhanced at high protein concentrations. This fraction appears to contain a soluble high-molecular-weight factor that modifies the specificity of the fatty acid synthetase complex for termination of the growing acyl chain.
Authors:
C R Strong; E M Carey; R Dils
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  The Biochemical journal     Volume:  132     ISSN:  0264-6021     ISO Abbreviation:  Biochem. J.     Publication Date:  1973 Jan 
Date Detail:
Created Date:  1973-10-09     Completed Date:  1973-10-09     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2984726R     Medline TA:  Biochem J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  121-3     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Carbon Isotopes
Cytosol / metabolism
Fatty Acid Synthetase Complex / metabolism
Fatty Acids / biosynthesis*
Female
Lactation*
Mammary Glands, Animal / cytology,  metabolism*
Microsomes / metabolism
Molecular Weight
Pregnancy
Rabbits
Structure-Activity Relationship
Subcellular Fractions / metabolism
Ultrafiltration
Chemical
Reg. No./Substance:
0/Carbon Isotopes; 0/Fatty Acids; EC 6.-/Fatty Acid Synthetase Complex
Comments/Corrections

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