Document Detail

A synthesis of the C1-C15 domain of the halichondrins.
MedLine Citation:
PMID:  20548799     Owner:  NLM     Status:  Publisher    
A concise route to the C1-C15 domain of the halichondrins is described. The key reaction is the conversion of a furfuryl alcohol to a pyranone. The stereocenter of this pyranone serves as the starting point for the other 8 stereocenters.
Katrina L Jackson; James A Henderson; Jonathan C Morris; Hajime Motoyoshi; Andrew J Phillips
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Publication Detail:
Journal Detail:
Title:  Tetrahedron letters     Volume:  49     ISSN:  0040-4039     ISO Abbreviation:  -     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2010-7-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984819R     Medline TA:  Tetrahedron Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  2939-2941     Citation Subset:  -    
Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309-0215, USA.
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Grant Support
R01 CA110246-01A1//NCI NIH HHS; R01 CA110246-02//NCI NIH HHS; R01 CA110246-03//NCI NIH HHS; R01 CA110246-04//NCI NIH HHS; R01 CA110246-05//NCI NIH HHS

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