Document Detail


Sjögren's syndrome in patients with the CREST variant of progressive systemic scleroderma.
MedLine Citation:
PMID:  1787489     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twenty-three patients with the CREST (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, telangiectasia) variant of progressive systemic sclerosis, were clinically, histopathologically and serologically examined for the presence of Sjögren's syndrome (SS). Fourteen were found to be positive. No significant difference could be demonstrated between them and the remaining 9. Characteristics of patients with CREST were compared with those of 29 randomly chosen patients with primary SS. Parotid gland enlargement was more frequently present (p less than 0.01) in the latter than in the former. Virtually no patients with CREST with SS had antibodies to Ro(SSA)/La(SSB).
Authors:
A A Drosos; Y L Pennec; M Elisaf; A Lamour; N C Acritidis; J R Jouquan; H M Moutsopoulos; P Youinou
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  18     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  1991 Nov 
Date Detail:
Created Date:  1992-03-24     Completed Date:  1992-03-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1685-8     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, School of Medicine, Universita of Ioannina, Greece.
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MeSH Terms
Descriptor/Qualifier:
Autoantibodies / analysis
Calcinosis / complications
Esophageal Motility Disorders / complications
Extremities
Humans
Raynaud Disease / complications
Scleroderma, Localized / complications*
Scleroderma, Systemic / complications,  immunology
Sjogren's Syndrome / complications*
Skin Diseases / complications
Syndrome
Telangiectasis / complications
Chemical
Reg. No./Substance:
0/Autoantibodies
Comments/Corrections
Comment In:
J Rheumatol. 1993 Jan;20(1):203-4   [PMID:  8441158 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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