| Möbius syndrome in infant exposed to cocaine in utero. | |
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MedLine Citation:
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PMID: 8452605 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The pathophysiology of Möbius syndrome has been debated for decades. A vascular etiology is currently favored because it explains the wide clinical spectrum of this syndrome. An infant is reported who was born with Möbius syndrome after a pregnancy complicated by heavy maternal use of cocaine and alcohol. We speculate that cocaine-induced vasoconstriction at a critical time of cerebrovascular development produced a vascular disruption sequence leading to the Möbius syndrome. |
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Authors:
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P Kankirawatana; M B Tennison; O D'Cruz; R S Greenwood |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric neurology Volume: 9 ISSN: 0887-8994 ISO Abbreviation: Pediatr. Neurol. Publication Date: 1993 Jan-Feb |
Date Detail:
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Created Date: 1993-04-22 Completed Date: 1993-04-22 Revised Date: 2006-05-23 |
Medline Journal Info:
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Nlm Unique ID: 8508183 Medline TA: Pediatr Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 71-2 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of North Carolina School of Medicine, Chapel Hill 27599-7025. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cocaine / adverse effects* Facial Paralysis / chemically induced* Female Humans Infant, Newborn Pregnancy Prenatal Exposure Delayed Effects* Syndrome |
| Chemical | |
Reg. No./Substance:
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50-36-2/Cocaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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