Document Detail

Sjögren's syndrome: historical overview and clinical spectrum of disease.
MedLine Citation:
PMID:  1496158     Owner:  NLM     Status:  MEDLINE    
Sjögren's syndrome is a chronic autoimmune and inflammatory disease characterized by lymphocyte proliferation that progressively destroys exocrine glands. The lymphocytes can infiltrate other and more vital organs and may at times become malignant. Another name for this disease is autoimmune exocrinopathy. It was first described over 100 years ago both as a benign syndrome of oral and ocular dryness and also as a lymphoid malignancy. Thus, Sjögren's syndrome is related to the autoimmune rheumatic diseases, as well as to lymphoid B-cell malignancies.
N Talal
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Publication Detail:
Type:  Historical Article; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Rheumatic diseases clinics of North America     Volume:  18     ISSN:  0889-857X     ISO Abbreviation:  Rheum. Dis. Clin. North Am.     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1992-09-10     Completed Date:  1992-09-10     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8708093     Medline TA:  Rheum Dis Clin North Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  507-15     Citation Subset:  IM; Q    
Department of Medicine, University of Texas Health Science Center, San Antonio.
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MeSH Terms
Diagnosis, Differential
History, 19th Century
History, 20th Century
Sjogren's Syndrome / complications,  diagnosis*,  history*
Grant Support

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