Document Detail


Sjögren's syndrome, cavitating lung disease and high sustained levels of antibodies to serine proteinase 3.
MedLine Citation:
PMID:  11028851     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case is described involving Sjögren's syndrome, high sustained levels of antibodies to serine proteinase 3, and cavitating lung disease. Possible diagnoses accounting for this unusual combination include a novel association of Sjögren's syndrome and Wegener's granulomatosis (suggested by the high and sustained levels of antibodies to serine proteinase 3) or a rare presentation of bronchiolitis obliterans organising pneumonia. Identification of the true nature of the patients illness facilitated more active management and a swift resolution of the clinical problem.
Authors:
C Young; S Hunt; A Watkinson; H Beynon
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Scandinavian journal of rheumatology     Volume:  29     ISSN:  0300-9742     ISO Abbreviation:  Scand. J. Rheumatol.     Publication Date:  2000  
Date Detail:
Created Date:  2000-10-25     Completed Date:  2000-10-25     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0321213     Medline TA:  Scand J Rheumatol     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  267-9     Citation Subset:  IM    
Affiliation:
Department of Rheumatology, Royal Free Hospital, London, UK. charles.young@ic.ac.uk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Anti-Bacterial Agents
Antibodies, Antineutrophil Cytoplasmic / blood
Autoantibodies / blood*
Cryptogenic Organizing Pneumonia / complications,  diagnosis*,  drug therapy
Diagnosis, Differential
Drug Therapy, Combination / therapeutic use
Female
Humans
Lung / pathology*,  radiography
Radiography, Thoracic
Serine Endopeptidases / immunology*
Sjogren's Syndrome / blood,  diagnosis*,  immunology
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Antibodies, Antineutrophil Cytoplasmic; 0/Autoantibodies; EC 3.4.21.-/Serine Endopeptidases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Sudden death and Wegener's granulomatosis of the pituitary.
Next Document:  Intracutaneous injection of lysophosphatidylcholine induces skin inflammation and accumulation of le...