Document Detail


Möbius syndrome as a syndrome of rhombencephalic maldevelopment: a case report.
MedLine Citation:
PMID:  19326837     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Möbius syndrome is a rare congenital disorder characterized by congenital facial weakness with impairment of ocular abduction. It is considered as a rhombencephalic disorder, and is often accompanied with hypoplasia of the pons and cerebellum. Here we report a male infant who had congenital facial asymmetry with absence of right-sided expression. Evident developmental delay was also found. The bilateral auditory brain stem response showed no response at 85dB. A reconstructive brain magnetic resonance imaging (MRI) revealed the absence of the right facial nerve as well as hypoplasia of the pons and cerebellum of the same side. Some voluntary contraction over the patient's right lower face was noted after facial muscle electrical stimulation.
Authors:
Hsueh-Ting Huang; Chiao-Wen Hwang; Ping-Hong Lai; Chu-Chin Chen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatrics and neonatology     Volume:  50     ISSN:  1875-9572     ISO Abbreviation:  -     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-03-30     Completed Date:  2009-04-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101484755     Medline TA:  Pediatr Neonatol     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  36-8     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Cerebellum / abnormalities
Facial Nerve / abnormalities
Humans
Infant, Newborn
Magnetic Resonance Imaging
Male
Mobius Syndrome / diagnosis,  pathology*
Pons / abnormalities
Rhombencephalon / abnormalities*

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