Document Detail


Menière's symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct: an analysis of a causal relationship between otosclerosis and Menière's disease.
MedLine Citation:
PMID:  2321690     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An association between otosclerosis and Menière's disease has been proposed on both a clinical and temporal bone histopathologic basis for well over three-quarters of a century. Controversy persists over a causal relationship between these two entities, however, and the underlying pathophysiologic mechanisms relating capsular otosclerosis with Menière's disease remain speculative. The first case of total, bilateral endolymphatic duct occlusion resulting from extensive capsular otosclerosis is presented in a woman manifesting Menière's symptoms. The severe endolymphatic hydrops resulting from otosclerotic endolymphatic duct occlusion is given as histopathologic proof of a causal relationship between these two entities. Analysis of 18 of our own temporal bone cases of extensive capsular otosclerosis without endolymphatic hydrops and review of the literature indicates the uniqueness of such a firm causal relationship in the present case.
Authors:
D J Franklin; A Pollak; U Fisch
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of otology     Volume:  11     ISSN:  0192-9763     ISO Abbreviation:  Am J Otol     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1990-05-10     Completed Date:  1990-05-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7909513     Medline TA:  Am J Otol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  135-40     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology, Baylor College of Medicine, Houston, Texas.
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MeSH Terms
Descriptor/Qualifier:
Adult
Endolymphatic Duct / pathology*
Female
Humans
Meniere Disease / etiology*,  pathology
Otosclerosis / complications*,  pathology
Temporal Bone / pathology*
Vestibule, Labyrinth / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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