Document Detail


A sweet tooth as the root cause of cardiac arrest.
MedLine Citation:
PMID:  19812810     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 71-year-old woman was admitted with hypotension and bradycardia. An electrocardiogram showed flattened T waves and increased U wave prominence, resulting in a long QT(U) syndrome. Her initial serum potassium level was 1.6 mmol/L (all other electrolytes, including magnesium, were normal). She suffered recurrent ventricular tachycardia and ventricular fibrillation arrest requiring direct current cardioversion and high-dose intravenous potassium chloride replacement. Systematic enquiry revealed that she had been constipated for a number of months and had resorted to consuming large quantities of liquorice on a daily basis for its laxative effects. Endocrinology review identified no primary abnormality of the renin- angiotensin- aldosterone axis, and the patient was diagnosed with hypokalemia secondary to liquorice overindulgence. Liquorice has a mineralocorticoid effect. If chronically consumed in large quantities, this effect may lead to severe depletion of whole-body potassium stores. The present case highlights a rare but important cause of hypokalemic cardiac arrest of which all acute care physicians should be aware.
Authors:
Andrew M Crean; Saif-El-Dean T Abdel-Rahman; John Pierre Greenwood
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  25     ISSN:  1916-7075     ISO Abbreviation:  Can J Cardiol     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-08     Completed Date:  2009-10-27     Revised Date:  2010-10-04    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  e357-8     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Toronto General Hospital, Toronto, Ontario. andrew.crean@uhn.on.ca
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MeSH Terms
Descriptor/Qualifier:
Aged
Electrocardiography
Female
Glycyrrhiza / adverse effects*
Heart Arrest / diagnosis,  etiology*
Humans
Hypokalemia / chemically induced*,  complications*,  physiopathology
Long QT Syndrome / complications*,  diagnosis
Plants, Medicinal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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