Document Detail

The surgical treatment of hyperinsulinism in infancy and childhood.
MedLine Citation:
PMID:  6317136     Owner:  NLM     Status:  MEDLINE    
Hyperinsulinaemic hypoglycaemia in infancy may be transient or persistent. Persistent hypoglycaemia is caused by nesidioblastosis of the pancreas, a diffuse pancreatic endocrine abnormality involving all the endocrine tissue, or by an islet cell adenoma. The cause of nesidioblastosis is not known but unless controlled its hypoglycaemic effects lead to convulsions, mental retardation or death. Patients with transient hyperinsulinaemic hypoglycaemia, and some with persistent hypoglycaemia, respond to medical therapy but those with an adenoma and many of those with nesidioblastosis will require partial or total pancreatectomy. The surgical treatment of six infants and a child is discussed. Five infants had nesidioblastosis; one infant and one nine-year-old girl had an islet cell adenoma. It is suggested that in the very young when there is no evidence of an insulinoma, resection at the initial operation should be greater--up to 90 per cent--than the previously recommended 75 per cent.
M H Gough
Related Documents :
8987096 - Mortality trends by cause of death in england and wales 1980-94: the impact of introduc...
11700196 - Parathyroid hyperplasia: an unusual cause of neonatal hypercalcemia.
22414886 - The patent ductus arteriosus in term infants, children, and adults.
16690236 - Fatal candida tropicalis infection in an 8-month-old infant with an aplasia of the thym...
10214606 - Breast feeding and later psychosocial adjustment.
9084126 - Toddlers' acquisition of self/other knowledge: ecological and interpersonal aspects of ...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The British journal of surgery     Volume:  71     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  1984 Jan 
Date Detail:
Created Date:  1984-02-21     Completed Date:  1984-02-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  75-8     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adenoma, Islet Cell / complications,  surgery
Hyperinsulinism / etiology,  surgery*
Infant, Newborn
Pancreatectomy / methods
Pancreatic Diseases / complications,  surgery
Pancreatic Neoplasms / complications,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Orchiectomy alone for Stage I testicular non-seminoma. A progress report on the Royal Marsden Hospit...
Next Document:  Neuropathological studies on the toxic syndrome related to adulterated rapeseed oil in Spain.