| Is the surgical repair of unruptured atherosclerotic aneurysms at a higher risk of intraoperative ischemia? | |
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MedLine Citation:
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PMID: 21095056 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: The incidence of ischemia might be increased in the surgical repair of atherosclerotic unruptured aneurysms compared to non-atherosclerotic aneurysms. The atherosclerotic wall might increase the occurrence of thrombembolic events or its rigidity might endanger the occlusion of perforators within the aneurysm vicinity. METHODS: 87 patients (53 patients without and 34 patients with atherosclerotic unruptured aneurysms, 50.5±9.7 years) were analyzed for severity of atherosclerosis within the aneurysm and the aneurysm bearing vessel, surgical maneuvers, intraoperative alterations in evoked potentials and clinical and neuroradiological results. RESULTS: Temporary vessel occlusion (25% vs. 50%, p=0.021), repositioning of a permanent clip (21% vs. 56%, p=0.001) and aneurysm remnants (2% vs. 18%, p=0.012) occurred more often in patients with atherosclerotic aneurysms. At 6 months, 3/34 patients with atherosclerosis (8.8%) had an unfavorable outcome, all patients without atherosclerosis had a favorable outcome (p=0.056). CONCLUSION: The surgical repair of unruptured aneurysms is safe but patients with atherosclerotic altered vessels and aneurysms accounted to a minor increase in unfavorable outcome and an increased risk of morbidity at 6 months postoperatively. This factor should be taken into consideration when performing surgery of atherosclerotic, unruptured aneurysms. |
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Authors:
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Andrea Szelényi; Jürgen Beck; Reinhard Strametz; Stella Blasel; Agi Oszvald; Andreas Raabe; Volker Seifert |
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Publication Detail:
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Type: Journal Article Date: 2010-11-20 |
Journal Detail:
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Title: Clinical neurology and neurosurgery Volume: 113 ISSN: 1872-6968 ISO Abbreviation: Clin Neurol Neurosurg Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7502039 Medline TA: Clin Neurol Neurosurg Country: Netherlands |
Other Details:
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Languages: eng Pagination: 129-35 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Department for Neurosurgery, Johann Wolfgang Goethe-University Hospital, Frankfurt, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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