Document Detail


The superior QRS axis in ostium primum ASD: a proposed mechanism.
MedLine Citation:
PMID:  125536     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The influence of abnormal hemodynamics, ventricular hypertrophy, and right bundle branch block on the AQRS was studied pre- and post-operatively in 29 patients with OPSD. The AQRS markedly diminishes with the surgical correction of abnormal hemodynamics and the subsequent resolution of RVH or BVH. With the persistence of ventricular hypertrophy postoperatively or the surgical induction of RBBB, the AQRS either remains unchanged or, in the latter instance, becomes more superior and rightward. The dependence of the superior AQRS on these factors suggests that a left anterior hemiblock is not responsible for this AQRS. In OPSD early activation of the posterobasal region of the left ventricle through an abnormally short posterior fascicle results in a minimal superior AQRS which is then exaggerated in the presence of abnormal hemodynamics, ventricular hypertrophy, or RBBB. Thus, the superior AQRS in OPSD with associated RBBB does not represent a true bifascicular block and has a different natural history and clinical significance.
Authors:
A M Borkon; D R Pieroni; P J Varghese; C S Ho; R D Rowe
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  90     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1975 Aug 
Date Detail:
Created Date:  1975-11-01     Completed Date:  1975-11-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  215-21     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Animals
Atrioventricular Node / physiopathology
Bundle-Branch Block / physiopathology
Cardiac Volume
Cardiomegaly / physiopathology
Child
Dogs
Electrocardiography*
Female
Heart Catheterization
Heart Conduction System / physiopathology*
Heart Septal Defects, Atrial / physiopathology*
Hemodynamics
Humans
Male
Myocardial Contraction
Vectorcardiography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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