| A successfully treated case of disseminated tuberculosis-associated hemophagocytic syndrome and multiple organ dysfunction syndrome. | |
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MedLine Citation:
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PMID: 11576906 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report the case of a patient who presented with disseminated tuberculosis-associated hemophagocytic syndrome (HPS). A 40-year-old man was admitted because of fatigue, fever, and renal dysfunction. Chest radiograph and computed tomography scan showed diffuse reticulonodular shadow, and Mycobacterium tuberculosis was identified. Peripheral blood counts decreased rapidly, and bone marrow aspiration revealed hemophagocytosis by macrophages. Despite antituberculous and steroid pulse therapy, multiple organ dysfunction syndrome developed. After plasma exchange and continuous hemodiafiltration were started, hypercytokinemia and vital signs improved dramatically. Although disseminated tuberculosis-associated HPS carries a poor prognosis, acute blood purification may be an effective means of treating HPS involving multiple organ dysfunction syndrome. |
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Authors:
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S Goto; I Aoike; Y Shibasaki; T Morita; S Miyazaki; T Shimizu; M Suzuki |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of kidney diseases : the official journal of the National Kidney Foundation Volume: 38 ISSN: 1523-6838 ISO Abbreviation: Am. J. Kidney Dis. Publication Date: 2001 Oct |
Date Detail:
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Created Date: 2001-09-28 Completed Date: 2001-10-18 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8110075 Medline TA: Am J Kidney Dis Country: United States |
Other Details:
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Languages: eng Pagination: E19 Citation Subset: IM |
Affiliation:
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Departments of Medicine, Pathology, and Surgery, Shinrakuen Hospital, Niigata, Japan. gotos@med.niigata-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Humans Male Phagocytosis / physiology* Respiration, Artificial Syndrome Tuberculosis, Miliary / complications, drug therapy*, physiopathology |
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