| The successful treatment of prurigo pigmentosa with macrolide antibiotics. | |
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MedLine Citation:
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PMID: 11244235 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Recent studies have demonstrated that macrolide antibiotics have anti-inflammatory as well as antibacterial effects. Therefore, macrolide antibiotics have been successfully used to treat patients with various inflammatory diseases. We evaluated the effect of macrolide antibiotics in 4 patients with prurigo pigmentosa who were treated with either 400 mg of clarithromycin or 300 mg of roxythromycin daily. Eruption and pruritus disappeared within a week in all the patients while those symptoms were unresponsive to other drugs. Although the mechanism of this effect remains unclear in patients with prurigo pigmentosa, macrolide antibiotics can be considered as an alternative treatment for prurigo pigmentosa. |
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Authors:
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N Yazawa; H Ihn; K Yamane; T Etoh; K Tamaki |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Dermatology (Basel, Switzerland) Volume: 202 ISSN: 1018-8665 ISO Abbreviation: Dermatology (Basel) Publication Date: 2001 |
Date Detail:
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Created Date: 2001-03-13 Completed Date: 2001-05-17 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9203244 Medline TA: Dermatology Country: Switzerland |
Other Details:
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Languages: eng Pagination: 67-9 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Faculty of Medicine, University of Tokyo, Japan. yazawa-DER@h.u-tokyo.ac.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Bacterial Agents / therapeutic use* Clarithromycin / therapeutic use Female Humans Male Middle Aged Pigmentation Disorders / drug therapy*, pathology Prurigo / drug therapy*, pathology Roxithromycin / therapeutic use Skin / drug effects, pathology Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 80214-83-1/Roxithromycin; 81103-11-9/Clarithromycin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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