Document Detail

A successful implementation of e-epidemiology: the Danish pregnancy planning study 'Snart-Gravid'.
MedLine Citation:
PMID:  20148289     Owner:  NLM     Status:  MEDLINE    
The attraction of being able to use the internet for the recruitment of an epidemiologic cohort stems mainly from cost efficiency and convenience. The pregnancy planning study ('Snart-Gravid')-a prospective cohort study of Danish women planning a pregnancy-was conducted to evaluate the feasibility and cost efficiency of using internet-based recruitment and follow-up. Feasibility was assessed by examining patient accrual data over time, questionnaire-specific response rates and losses to follow-up. The relative cost efficiency was examined by comparing the study costs with those of an alternative non internet-based study approach. The target recruitment of 2,500 participants over 6 months was achieved using advertisements on a health-related website, supported by a coordinated media strategy at study initiation. Questionnaire cycle-specific response rates ranged from 87 to 90% over the 12-month follow-up. At 6 months, 87% of women had a known outcome or were still under follow-up; at 12 months the figure was 82%. The study cost of $400,000 ($160 per enrolled subject) compared favorably with the estimated cost to conduct the same study using a conventional non-internet based approach ($322 per subject). The gain in efficiency with the internet-based approach appeared to be even more substantial with longer follow-up and larger study sizes. The successful conduct of this pilot study suggests that the internet may be a useful tool to recruit and follow subjects in prospective cohort studies.
Krista F Huybrechts; Ellen M Mikkelsen; Tina Christensen; Anders H Riis; Elizabeth E Hatch; Lauren A Wise; Henrik Toft Sørensen; Kenneth J Rothman
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2010-02-11
Journal Detail:
Title:  European journal of epidemiology     Volume:  25     ISSN:  1573-7284     ISO Abbreviation:  Eur. J. Epidemiol.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-07     Completed Date:  2010-08-06     Revised Date:  2011-07-28    
Medline Journal Info:
Nlm Unique ID:  8508062     Medline TA:  Eur J Epidemiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  297-304     Citation Subset:  IM    
Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA.
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MeSH Terms
Cohort Studies
Contraception Behavior* / statistics & numerical data
Cost-Benefit Analysis
Data Collection / methods
Epidemiologic Studies*
Feasibility Studies
Patient Selection
Prospective Studies
Research Design*
Sexual Behavior / statistics & numerical data
Young Adult
Grant Support
R21 HD050264-02/HD/NICHD NIH HHS; R21050264//PHS HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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