Document Detail


A study to compare disease-specific quality of life with clinical anatomical and hemodynamic assessments in patients with varicose veins.
MedLine Citation:
PMID:  21129895     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The wide variety of outcome measures to evaluate patients with varicose veins poses significant difficulties when comparing clinical trials. In addition, the relationship between different outcome measures is poorly understood. The aim of this study was to compare anatomical, hemodynamic, and clinical outcomes with disease-specific quality-of-life tools in patients undergoing treatment for varicose veins.
METHODS: Patients undergoing treatment for symptomatic veins in a single unit were studied. Assessments included duplex ultrasonography, digital photoplethysmography, evaluation of Venous Clinical Severity Scores and CEAP scores, generic (Short Form 12 [SF12]) and disease-specific (Aberdeen Varicose Vein Questionnaire [AVVQ], and Specific Quality-of-life and Outcome Response-Venous [SQOR-V]) questionnaires. Patients were reviewed at 6 weeks when hemodynamic, clinical, and quality-of-life assessments were repeated. The relationships between these outcomes were assessed.
RESULTS: The AVVQ showed a strong positive correlation with the SQOR-V (Spearman coefficient 0.702; P < .001) and weaker, but significant correlations with the SF12 physical and mental component scores and the Venous Clinical Severity Score (VCSS) (P < .001, P = .019, and P < .001, respectively, Spearman correlation). No correlations were observed between the AVVQ and photoplethysmography results (Spearman coefficient -0.042; P = .606), and weak correlations were observed with the AVVQ and anatomical reflux. At 6 weeks, functional, clinical, and hemodynamic measurements were all responsive to changes following interventions; however, correlations observed between changes in disease-specific quality-of-life and generic, clinical, and hemodynamic outcomes were weak.
CONCLUSIONS: Both the AVVQ and SQOR-V questionnaire are sensitive and responsive disease-specific questionnaires, which correlate with generic and clinical outcomes to some extent. Anatomical and hemodynamic measurements correlated poorly with functional outcomes both preoperatively and following interventions.
Authors:
Amanda C Shepherd; Manj S Gohel; Chung S Lim; Alun H Davies
Related Documents :
11869655 - The epley (canalith repositioning) manoeuvre for benign paroxysmal positional vertigo.
11279705 - Moderately early (7-14 days) postnatal corticosteroids for preventing chronic lung dise...
20238355 - Glucocorticoids for the treatment of anaphylaxis.
18793915 - Flare-ups after endodontic treatment: a meta-analysis of literature.
9139555 - Treatment of shigellosis: v. comparison of azithromycin and ciprofloxacin. a double-bli...
24937655 - Prognostic value of neuropeptide proenkephalin a in patients with severe traumatic brai...
Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2010-12-03
Journal Detail:
Title:  Journal of vascular surgery     Volume:  53     ISSN:  1097-6809     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-31     Completed Date:  2011-03-10     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  374-82     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.
Affiliation:
4 East Department of Vascular Surgery, Imperial Vascular Unit, Imperial College London, Charing Cross Hospital, London W6 8RF, United Kingdom.
Data Bank Information
Bank Name/Acc. No.:
ISRCTN/ISRCTN66818013
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Catheter Ablation
Female
Hemodynamics*
Humans
Laser Therapy
London
Male
Middle Aged
Photoplethysmography
Predictive Value of Tests
Quality of Life*
Questionnaires
Severity of Illness Index
Time Factors
Treatment Outcome
Ultrasonography, Doppler, Color
Varicose Veins / diagnosis*,  pathology,  physiopathology,  psychology,  surgery
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Venous thoracic outlet syndrome secondary to first rib osteochondroma in a pediatric patient.
Next Document:  Creating functional autogenous vascular access in older patients.