Document Detail

A study of seven different types of grafts for jugular vein transplantation in the horse.
MedLine Citation:
PMID:  15893349     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to investigate the biological behaviour of vascular grafts replacing a section of the jugular vein in order to improve the results of the surgical treatment of complete thrombosis of the jugular vein in the horse. Seven graft types: fresh allograft, home frozen allograft, glutaraldehyde-fixed allograft, cryo-preserved allograft, PTFE-graft (Gore), small intestinal submucosa preparation (Cook) and fresh autograft, were randomly implanted in ponies. The grafts were removed after one month and examined histologically for: preservation of the graft structures, acceptance by the host, intima proliferation, presence of endothelium and patency. The glutaraldehyde- and cryopreserved grafts show reasonable results and the PTFE and autograft had the best results especially with respect to host acceptance, endothelium presence and patency. Further research is necessary to improve graft behaviour, especially to the aspect of endothelisation. Obstruction of the jugular vein in horses can be treated surgically.
P Wiemer; E Gruys; B van Hoeck
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Research in veterinary science     Volume:  79     ISSN:  0034-5288     ISO Abbreviation:  Res. Vet. Sci.     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-08-01     Completed Date:  2005-11-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401300     Medline TA:  Res Vet Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  211-7     Citation Subset:  IM    
Equine Section, De Lingehoeve, Lienden, The Netherlands.
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MeSH Terms
Horse Diseases / pathology,  surgery*
Horses / surgery
Jugular Veins / transplantation*
Random Allocation
Thrombosis / pathology,  surgery*,  veterinary*
Tissue Transplantation / classification,  methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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