Document Detail

The study of serum apoprotein levels as indicators for the severity of angiographically assessed coronary artery disease.
MedLine Citation:
PMID:  2014787     Owner:  NLM     Status:  MEDLINE    
Serum apoprotein A-I (Apo A-I) and B (Apo-B) concentrations were determined in 40 subjects undergoing coronary angiography for past myocardial infarction and angina pectoris, and the authors studied the relationship between the apoprotein concentrations and the severity of coronary artery disease (CAD). During this study, serum total cholesterol, triglyceride, and high-density lipoprotein, low-density lipoprotein, and very low density lipoprotein cholesterol concentrations were determined to control analysis. The results showed that the decrease in serum Apo A-I levels was the best indicator distinguishing CAD from non-coronary artery disease; the Apo B/Apo A-I ratio had the most consistent association with the severity of CAD as assessed by angiography; Apo B/Apo A-I values ranging from 0.98 to 1.00 might be considered critical values for early CAD.
Q X Pan; P Liu; S C Wang; J T Pan; B Y Sun; X Y Wu; A Saltups
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  95     ISSN:  0002-9173     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-05-10     Completed Date:  1991-05-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  597-600     Citation Subset:  AIM; IM    
Department of Cardiology, Shandong Medical University, Jinan, People's Republic of China.
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MeSH Terms
Apoproteins / blood*
Arteriosclerosis / blood,  pathology
Cholesterol / blood
Coronary Disease / blood,  radiography*
Lipoproteins, HDL / blood
Lipoproteins, LDL / blood
Middle Aged
Severity of Illness Index
Triglycerides / blood
Reg. No./Substance:
0/Apoproteins; 0/Lipoproteins, HDL; 0/Lipoproteins, LDL; 0/Triglycerides; 57-88-5/Cholesterol

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