Document Detail

A study of prevalence of Chlamydia trachomatis infection in women with first trimester pregnancy losses.
MedLine Citation:
PMID:  15027756     Owner:  NLM     Status:  MEDLINE    
The study included 125 patients in the first trimester of pregnancy, who were divided into group A (50 control subjects with normal intrauterine pregnancy), Group B (50 patients with spontaneous abortion), group C (25 patients with ectopic pregnancy). All the patients were investigated including routine blood and urine tests and special tests related to the cause of pregnancy loss. The patients were tested for IgG antibodies to Chlamydia trachomatis by ELISA technique and conjunctival smear were tested for presence of inclusion bodies to C. trachomatis. It was concluded that C. trachomatis is one of the important cause of spontaneous abortion and ectopic pregnancy. It is highly prevalent in our population, the prevalence being 10% in group A, 26% in group B, 28% in group C. Conjunctival smear showed presence of inclusion bodies in 0.8% patients. With abortions then risk of lower genital tract chlamydia infection spreading to upper genital tract increases. ELISA for C. trachomatis should be done when women are being investigated for the cause of spontaneous abortion and ectopic pregnancy.
Kumkum Avasthi; Tamanna Garg; Shweta Gupta; R K Grewal; Shobha Ram
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of pathology & microbiology     Volume:  46     ISSN:  0377-4929     ISO Abbreviation:  Indian J Pathol Microbiol     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2004-03-18     Completed Date:  2004-04-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7605904     Medline TA:  Indian J Pathol Microbiol     Country:  India    
Other Details:
Languages:  eng     Pagination:  133-6     Citation Subset:  IM    
Department of Obst. & Gynae, DMC&H, Ludhiana.
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MeSH Terms
Abortion, Spontaneous / etiology*
Antibodies, Bacterial / blood
Chlamydia Infections / complications,  epidemiology*
Chlamydia trachomatis* / immunology
Immunoglobulin G / blood
Pregnancy Complications, Infectious / epidemiology*
Pregnancy Trimester, First
Reg. No./Substance:
0/Antibodies, Bacterial; 0/Immunoglobulin G

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