Document Detail


A study on pathogenesis and therapy of hemorrhagic fever with renal syndrome
MedLine Citation:
PMID:  1356714     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
581 early cases of typical hemorrhagic fever with renal syndrome (HFRS) were dynamically studied on the clinical manifestations and laboratory findings from 1986 to 1989. All the patients were treated with various methods. The results showed: (1) The manifestations of microvascular damage, proteinuria and thrombocytopenia can be found at the first day of the onset in 80.0%, 72.2% and 33.3% respectively. In a word, the characteristic features of HFRS appear at the onset of the disease. (2) In 446 early cases the initial severity of the disease corresponded with the final severity at a rate of 89.2%; it indicated that the damage of HFRS may result from the first attack. (3) The time of the onset, peak and persistence of all the characteristic features were similar; it is suggested that the course of HFRS may be self-limited. (4) Based on the clinical understanding and the effective results in the 446 early cases treated with fluid therapy alone, we consider that the effective treatment of HFRS is early and reasonable fluid therapy.
Authors:
D P Yu; G Q Wang; M C Liu
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Zhonghua nei ke za zhi [Chinese journal of internal medicine]     Volume:  31     ISSN:  0578-1426     ISO Abbreviation:  Zhonghua Nei Ke Za Zhi     Publication Date:  1992 Mar 
Date Detail:
Created Date:  1992-11-04     Completed Date:  1992-11-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  16210490R     Medline TA:  Zhonghua Nei Ke Za Zhi     Country:  CHINA    
Other Details:
Languages:  chi     Pagination:  163-6, 189     Citation Subset:  IM    
Affiliation:
Department of Infections Diseases, First Affiliated Hospital of Harbin Medical University.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Female
Fluid Therapy
Hemorrhagic Fever with Renal Syndrome / etiology*,  therapy*
Humans
Male
Middle Aged
Proteinuria / etiology
Thrombocytopenia / etiology
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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