| A study of the optimum bacteriostatic action of a synthetic medicine on bacteria using a microcalorimetric method. | |
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MedLine Citation:
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PMID: 8877116 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The growth thermograms of strain 6, 2b, 3b, 5b, 1a, x, and y of Shigella flexneri with the inhibitory action of a synthetic medicine were determined by using the 2277 thermal activity monitor. Using a microorganism growth model with inhibitory conditions, the specific growth rate (mu) at different concentrations (c) of a synthetic medicine were calculated and the mu approximately c equations were established. From these mu approximately c equations, the concentration of the synthetic medicine with which the specific growth rate was minimum could be calculated. Therefore, we can analyze the bacteriostatic action of the synthetic medicine on these bacteria. |
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Authors:
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Y Liu; Z Nan; H Sun; H Zhang; P Gao |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Chinese journal of biotechnology Volume: 12 ISSN: 1042-749X ISO Abbreviation: Chin. J. Biotechnol. Publication Date: 1996 |
Date Detail:
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Created Date: 1997-02-03 Completed Date: 1997-02-03 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9100855 Medline TA: Chin J Biotechnol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 61-5 Citation Subset: IM |
Affiliation:
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Department of Chemistry, Qufu Normal University, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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pharmacology* Calorimetry / methods* Dose-Response Relationship, Drug Organometallic Compounds / pharmacology Semicarbazides / pharmacology Shigella flexneri / drug effects* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/N-methyl-N-1,3,4-thiazole-salicylthiosemicarbazide-cobalt(II); 0/Organometallic Compounds; 0/Semicarbazides |
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