Document Detail

A study of the factors responsible for the development of allergic diseases in early life.
MedLine Citation:
PMID:  15997868     Owner:  NLM     Status:  MEDLINE    
In order to analyze the determinants involved in the development of allergic diseases early in infancy, we examined the environmental and genetic factors that might affect the induction of such diseases during infancy, using a questionnaire. Maternal pharyngitis during pregnancy was significantly related to the development of atopic dermatitis in their progeny. Moreover, the frequency of the maternal infection was associated with a significantly increased risk of allergy in their infants. The prevalence of post-delivery maternal allergy was positively linked to the allergic symptoms in their children while the likelihood of bearing allergic children was related to the numbers of allergic individuals within their family. These results suggested that pre- and post-natal maternal factors and any genetic predisposition might modify the development of allergy in infancy.
Yutaka Kawano; Miki Morikawa; Misa Watanabe; Akihiro Ohshiba; Takeshi Noma; Hiroshi Odajima
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Asian Pacific journal of allergy and immunology / launched by the Allergy and Immunology Society of Thailand     Volume:  23     ISSN:  0125-877X     ISO Abbreviation:  Asian Pac. J. Allergy Immunol.     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-07-06     Completed Date:  2006-04-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8402034     Medline TA:  Asian Pac J Allergy Immunol     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  1-6     Citation Subset:  IM    
Department of Pediatrics, Yokohama City Minato Red Cross Hospital, Yokohama, Japan.
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MeSH Terms
Asthma / epidemiology,  etiology*
Dermatitis, Atopic / epidemiology,  etiology*
Family Health
Hypersensitivity / epidemiology*,  genetics
Japan / epidemiology
Pharyngitis / epidemiology,  genetics,  immunology
Pregnancy Complications, Infectious / epidemiology,  genetics,  immunology
Prenatal Exposure Delayed Effects*
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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