Document Detail


A study on experimental cryptosporidiosis.
MedLine Citation:
PMID:  1431285     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cryptosporidium oocysts were isolated from stools of infected patients diagnosed as cryptosporidiosis. Suckling Swiss albino mice were infected orally by these oocysts in a dose of 10(6) oocysts/mouse. Mice were divided into 9 groups according to the duration of infection 2, 3, 4, 5, 6, 7, 10, 10, 15, 21 days postinfection, corresponding non infected control groups were included. Stools of infected mice were examined twice daily to determine; infection rate, prepatent period and intensity of infection. Mice were sacrificed according to the schedule and the whole intestine was isolated and processed for histopathological examination by H & E and modified Ziehl Nielsen stain, and histochemical examination for acid and alkaline phosphatase activity. The results revealed that the infection rate was 90% and prepatent period 3-5 days and the course of infection was 21 days. The maximum pathological changes were in the ileum. These changes were reversible.
Authors:
M M Youssef; S M Amin; L M Abou Samra; W M el-Gebaly; S M Hammam; E el Sabaawy; A M Khalifa
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Egyptian Society of Parasitology     Volume:  22     ISSN:  1110-0583     ISO Abbreviation:  J Egypt Soc Parasitol     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1992-12-22     Completed Date:  1992-12-22     Revised Date:  2013-05-02    
Medline Journal Info:
Nlm Unique ID:  8102141     Medline TA:  J Egypt Soc Parasitol     Country:  EGYPT    
Other Details:
Languages:  eng     Pagination:  667-74     Citation Subset:  IM    
Affiliation:
Department of Parasitology, Faculty of Medicine, Alexandria University, Egypt.
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MeSH Terms
Descriptor/Qualifier:
Animals
Animals, Suckling
Cryptosporidiosis / parasitology,  pathology*
Cryptosporidium / isolation & purification*
Feces / parasitology
Histocytochemistry
Intestines / parasitology,  pathology*
Mice

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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