| The study of dynamic response to acute hemorrhage by pulse spectrum analysis. | |
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MedLine Citation:
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PMID: 16710894 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Traditional Chinese Medicine (TCM) holds that blood and qi are fundamental substances in the human body for sustaining normal vital activity. The theory of qi, blood and zang-fu contribute the most important theoretical basis of human physiology in TCM. An animal model using conscious rats was employed in this study to further comprehend how organisms survive during acute hemorrhage by maintaining the functionalities of qi and blood through dynamically regulating visceral physiological conditions. Pulse waves of arterial blood pressure before and after the hemorrhage were taken in parallel to pulse spectrum analysis. Percentage differences of mean arterial blood pressure and harmonics were recorded in subsequent 5-minute intervals following the hemorrhage. Data were analyzed using a one-way analysis of variance (ANOVA) with Duncan's test for pairwise comparisons. Results showed that, within 30 minutes following the onset of acute hemorrhage,the reduction of mean arterial blood pressure was improved from 62% to 20%. Throughout the process, changes to the pulse spectrum appeared to result in a new balance over time. The percentage differences of the second and third harmonics, which were related to kidney and spleen, both increased significantly than baseline and towards another steady state. Apart from the steady state resulting from the previous stage, the percentage difference of the 4th harmonic decreased significantly to another steady state. The observed change could be attributed to the induction of functional qi, and is a result of qi-blood balancing activity that organisms hold to survive against acute bleeding. |
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Authors:
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Yu Hsin Chang; Chia I Tsai; Jaung Geng Lin; Yue Der Lin; Tsai Chung Li; Yi Chang Su |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of Chinese medicine Volume: 34 ISSN: 0192-415X ISO Abbreviation: Am. J. Chin. Med. Publication Date: 2006 |
Date Detail:
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Created Date: 2006-05-19 Completed Date: 2006-12-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7901431 Medline TA: Am J Chin Med Country: Singapore |
Other Details:
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Languages: eng Pagination: 449-60 Citation Subset: IM |
Affiliation:
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Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan, R.O.C. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Analysis of Variance Animals Hemorrhage / physiopathology* Male Rats Rats, Sprague-Dawley |
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