Document Detail


A study on continuous low-flow perfusion with low-potassium dextran for donor isolated lung preservation.
MedLine Citation:
PMID:  10322653     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To test the validity of continuous low-flow perfusion with low-potassium dextran (LPD) to preserve rabbit lung. METHODS: Isolated rabbit lungs were preserved for eight hours either in Ringer's solution by simple storage (Group I) or in continuous low-flow perfusion with LPD (Group II). After preservation, lung functions were assessed to compare these two methods. RESULTS: The water gain in Group I was higher than that in Group II. During reperfusion, the functional test values for the immersed lungs were lower than those for the perfused lungs. The lipid peroxidation product (MDA) was significantly decreased in perfused lungs during reperfusion. CONCLUSIONS: Low-flow perfusion with LPD is better than immersion for the lung preservation.
Authors:
H Qiu; C Liao; D Chen
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Publication Detail:
Type:  Comparative Study; In Vitro; Journal Article    
Journal Detail:
Title:  Chinese medical journal     Volume:  111     ISSN:  0366-6999     ISO Abbreviation:  Chin. Med. J.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1999-06-29     Completed Date:  1999-06-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7513795     Medline TA:  Chin Med J (Engl)     Country:  CHINA    
Other Details:
Languages:  eng     Pagination:  49-51     Citation Subset:  IM    
Affiliation:
Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou, China.
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MeSH Terms
Descriptor/Qualifier:
Animals
Dextrans*
Lung*
Male
Organ Preservation
Organ Preservation Solutions*
Perfusion
Potassium*
Rabbits
Chemical
Reg. No./Substance:
0/Organ Preservation Solutions; 7440-09-7/Potassium; 9004-54-0/Dextrans

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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