| A study comparing a gestoden triphasic formulation with a fixed combination OC. | |
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MedLine Citation:
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PMID: 2596365 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Metabolic parameters were studied in 30 patients over 12 treatment cycles in a double-blind randomized comparative trial of the new progestogen gestoden in a triphasic formulation against a fixed dose combination pill containing desogrestrel, in Bandung, Indonesia. The results of this laboratory experience affirm findings in similar previous metabolic studies that: (1) the changes induced by modern low-dose pills are clinically and statistically insignificant; (2) throughout the treatment cycles, the values of the various laboratory tests remain well within the normal range; and (3) the favorable balance between coagulation and fibrinolysis is maintained. Results of lipoprotein, coagulation, fibrinolytic and liver function tests in 27 patients are presented. Gestoden's pharmacologic profile and the worldwide clinical experience with the triphasic gestoden formulation in 4285 women are discussed. |
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Authors:
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T Agoestina; U Sabarudin; G Hoppe |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Advances in contraception : the official journal of the Society for the Advancement of Contraception Volume: 5 ISSN: 0267-4874 ISO Abbreviation: Adv Contracept Publication Date: 1989 Jun |
Date Detail:
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Created Date: 1990-01-25 Completed Date: 1990-01-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8607435 Medline TA: Adv Contracept Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 71-84 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Hasan Sadikin Hospital, University of Padjadgaran, Bandung, Indonesia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Coagulation
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drug effects Blood Pressure / drug effects Body Weight / drug effects Contraceptives, Oral / pharmacology* Contraceptives, Oral, Combined / adverse effects, pharmacology* Contraceptives, Oral, Sequential / adverse effects, pharmacology* Ethinyl Estradiol / pharmacology Female Humans Lipoproteins / analysis Liver / drug effects Liver Function Tests Norpregnenes / pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Contraceptives, Oral; 0/Contraceptives, Oral, Combined; 0/Contraceptives, Oral, Sequential; 0/Lipoproteins; 0/Norpregnenes; 57-63-6/Ethinyl Estradiol; 60282-87-3/Gestodene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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