Document Detail

A study of changes in homocysteine levels during normal pregnancy and pre-eclampsia.
MedLine Citation:
PMID:  18975508     Owner:  NLM     Status:  MEDLINE    
To find out changes in homocysteine levels that occur during normal pregnancy and pregnancy with pre-eclamptic toxaemia and also to find out correlation between homocysteine concentration and preeclamptic toxaemia a study was carried out among 90 women of which 30 were control which included normotensive non-pregnant women and the study group I comprised 30 pregnant normotensive women and the study group II comprised 30 pregnant women with pre-eclamptic toxaemia. Serum homocysteine was measured in all subjects using fluorescence polarisation immuno-assay. Control group had highest mean homocysteine levels while the study group I had least mean homocysteine levels (p < 0.001). Levels were significantly higher in subjects with BP > 146/100 mm Hg as compared to subjects with BP >140/90 and <146/100 mm Hg (p=0.017). There was significant difference between study group I and II at same gestational age. Hyperhomocysteinaemia was observed in pre-eclamptic females, also it was found that homocysteine levels were directly correlated with severity of pre-eclampsia.
Urmila Singh; H P Gupta; R K Singh; Manju Shukla; Ranjana Singh; Seema Sinha Nee Mehrotra; Shweta Prasad
Related Documents :
626728 - Risk of pre-term delivery in patients with previous pre-term delivery and/or abortion.
2390528 - Vitreous haemorrhage as a complication of hellp syndrome.
11372768 - Multivariate analysis of genetic and acquired factors; t235 variant of the angiotensino...
19076958 - Pulse wave analysis: a preliminary study of a novel technique for the prediction of pre...
21666088 - Ulipristal acetate: contraceptive or contragestive?
2512378 - The distribution of pregnancy-associated prostaglandin synthetase inhibitor in the huma...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Indian Medical Association     Volume:  106     ISSN:  0019-5847     ISO Abbreviation:  J Indian Med Assoc     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-11-03     Completed Date:  2008-12-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7505608     Medline TA:  J Indian Med Assoc     Country:  India    
Other Details:
Languages:  eng     Pagination:  503-5     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, King George's Medical University, Lucknow.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Case-Control Studies
Cross-Sectional Studies
Fluorescence Polarization
Homocysteine / blood*
Hyperhomocysteinemia / blood
Maternal Welfare*
Perinatal Care*
Pre-Eclampsia / blood*
Risk Factors
Young Adult
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Safety and tolerability of ramipril 10 mg in patients at high risk of cardiovascular events: an obse...
Next Document:  A study of distribution of ABO and Rh (D) blood groups amongst Sikkimese.