| A study of cardiovascular effects of Azadirachta indica (neem) on isolated perfused heart preparations. | |
| | |
MedLine Citation:
|
PMID: 12500501 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The effects of aqueous leaf extract of Azadirachta indica were evaluated on isolated prefused frog and rabbit heart. Dose dependent negative inotropic and chronotropic effects were observed in both the heart preparation. An increase in coronary blood flow in isolated rabbit heart was observed. The effects were not blocked by atropine and mepyramine in both the preparations. The data suggests that A. indica could be of benefit in coronary artery disease and arrhythmias. |
| | |
Authors:
|
P Khosla; A Gupta; J Singh |
Publication Detail:
|
Type: In Vitro; Journal Article |
Journal Detail:
|
Title: Indian journal of physiology and pharmacology Volume: 46 ISSN: 0019-5499 ISO Abbreviation: Indian J. Physiol. Pharmacol. Publication Date: 2002 Apr |
Date Detail:
|
Created Date: 2002-12-25 Completed Date: 2003-05-20 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0374707 Medline TA: Indian J Physiol Pharmacol Country: India |
Other Details:
|
Languages: eng Pagination: 241-4 Citation Subset: IM |
Affiliation:
|
Department of Pharmacology, Pt. B.D. Sharma PGIMS, Rohtak-124 001. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Azadirachta* Cardiovascular System / drug effects* Dose-Response Relationship, Drug Female Heart / drug effects*, physiology Male Plant Extracts / isolation & purification, pharmacology Plant Leaves Rabbits Ranidae |
| Chemical | |
Reg. No./Substance:
|
0/Plant Extracts |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Evaluation of analgesic, antipyretic and anti-inflammatory activity of spirobarbitunylphenothiazines...
Next Document: Serum profile of calcium, phosphorus and magnesium in crossbred heifers as influenced by gestation a...