| A study on the beryllium lymphocyte transformation test and the beryllium levels in working environment. | |
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MedLine Citation:
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PMID: 9248221 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The relationship between airborne concentration of beryllium in the working environment and workers' beryllium lymphocyte transformation test (Be-LTT) values was examined based on data obtained from a four-year survey (1992-1995) conducted at beryllium-copper alloy manufacturing factories. This study showed that the T cells of workers continuously exposed to beryllium of more than 0.01 microgram/m3 could be activated and that the cell-mediated immune response of workers could be promoted. On the other hand, the Be-LTT of workers exposed to beryllium levels of less than 0.01 microgram/m3 was shown to be unaffected by beryllium. These findings suggest that beryllium sensitization is not manifested when level of beryllium in working environment are less than 0.01 microgram/m3. Therefore, in such cases workers do not develop Chronic beryllium disease (CBD). We concluded that the Be-LTT can be applied as a medical indicator to detect the development of CBD. |
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Authors:
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T Yoshida; S Shima; K Nagaoka; H Taniwaki; A Wada; H Kurita; K Morita |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Industrial health Volume: 35 ISSN: 0019-8366 ISO Abbreviation: Ind Health Publication Date: 1997 Jul |
Date Detail:
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Created Date: 1997-09-23 Completed Date: 1997-09-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 2985065R Medline TA: Ind Health Country: JAPAN |
Other Details:
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Languages: eng Pagination: 374-9 Citation Subset: IM |
Affiliation:
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Department of Public Health, Fujita Health University School of Medicine, Aichi, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Air Pollutants, Occupational / adverse effects* Berylliosis / diagnosis Beryllium / adverse effects* Chronic Disease Environmental Monitoring Humans Industry Lymphocyte Activation / drug effects* Male Middle Aged Occupational Exposure / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Air Pollutants, Occupational; 7440-41-7/Beryllium |
| Comments/Corrections | |
Comment In:
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Ind Health. 1998 Oct;36(4):389-91
[PMID:
9810156
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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