| A study of P300 in melancholic depression--correlation with psychotic features. | |
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MedLine Citation:
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PMID: 8018798 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The relationship between delusions and hallucinations (psychotic features) in melancholic depression and auditory P300 was studied. Forty patients with melancholic depression as per DSM-III-R were studied, 20 of whom had hallucinations and/or delusions. The 20 patients of the two groups were individually matched on age, gender, sociodemographic variables, and psychopathology (except for psychotic features). Auditory P300 obtained by the "oddball paradigm" showed that those with hallucinations and/or delusions had a significantly smaller P3 amplitude. Significant correlations between "psychotic features" and P3 amplitude was found. Implications of these findings on research, classification, and management of depression have been outlined. |
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Authors:
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P J Santosh; S Malhotra; M Raghunathan; Y N Mehra |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Biological psychiatry Volume: 35 ISSN: 0006-3223 ISO Abbreviation: Biol. Psychiatry Publication Date: 1994 Apr |
Date Detail:
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Created Date: 1994-08-04 Completed Date: 1994-08-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0213264 Medline TA: Biol Psychiatry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 474-9 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acoustic Stimulation Adult Biological Markers Delusions / diagnosis*, physiopathology Depressive Disorder / classification, diagnosis*, physiopathology Diagnosis, Differential Electroencephalography* Evoked Potentials, Auditory / physiology* Female Hallucinations / diagnosis*, physiopathology Humans Male Middle Aged Psychiatric Status Rating Scales |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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