Document Detail

A study of 656 patients with "early" ovarian cancer.
MedLine Citation:
PMID:  6706234     Owner:  NLM     Status:  MEDLINE    
Six hundred fifty-six patients with epithelial ovarian cancer that had been totally excised macroscopically were analyzed with the intention of providing information for a prospective randomized trial of adjuvant therapy. No deaths occurred in patients with tumors of borderline malignancy or those with stage Ia(i) well-differentiated tumors and hence adjuvant therapy was not justified in these patients. Survival of patients with clear cell carcinoma was poor, irrespective of stage. No statistically significant difference was found between the various modalities of adjuvant treatment, but those patients who had no further treatment after primary surgery had a significantly better survival. No obvious factors were found to account for this result. It is concluded that a "no adjuvant treatment" group must be included in any prospective study.
D Guthrie; M L Davy; P R Philips
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Gynecologic oncology     Volume:  17     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  1984 Mar 
Date Detail:
Created Date:  1984-05-14     Completed Date:  1984-05-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  363-9     Citation Subset:  IM    
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MeSH Terms
Combined Modality Therapy
Middle Aged
Neoplasm Recurrence, Local / therapy
Neoplasm Staging
Ovarian Neoplasms / mortality,  radiotherapy,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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