Document Detail


The structural implications of a unilateral facial skeletal cleft: a three-dimensional finite element model approach.
MedLine Citation:
PMID:  18333648     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: For children born with a unilateral facial skeletal cleft, oral motor function is impaired and skeletal development and growth are asymmetrical with regard to the midsagittal plane. This study was designed to verify that a unilateral skeletal cleft and its dimensions (i.e., depth and width) affect the severity of the asymmetric stress and strain distribution within the maxilla. METHODS: A three-dimensional finite element model of a normal maxilla was developed from pediatric, subject-specific computerized tomography scan data. A clefting pattern then was introduced to simulate varying degrees of deformity in geometry, with the bone properties and boundary conditions held constant. The asymmetric index was introduced to quantify the asymmetrical stress and strain distribution within the maxilla with regard to the midsagittal plane. RESULTS: The unilateral skeletal cleft led to a nonuniform, asymmetric stress and strain distribution within the maxilla: intensified on the noncleft side and weakened on the cleft side. As the depth of the unilateral cleft increased, the stress and strain distribution became increasingly asymmetric as measured by the asymmetric index. In contrast, the width of the cleft had minimal effect on the asymmetrical stress and strain distribution. INTERPRETATION/CONCLUSION: These results implied that a child born with a unilateral cleft would be expected to have an asymmetric skeletal development between the noncleft and the cleft sides as a consequence of an asymmetric functional loading pattern.
Authors:
Linping Zhao; Jean E Herman; Pravin K Patel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association     Volume:  45     ISSN:  1055-6656     ISO Abbreviation:  Cleft Palate Craniofac. J.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-12     Completed Date:  2008-06-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102566     Medline TA:  Cleft Palate Craniofac J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  121-30     Citation Subset:  D; IM    
Affiliation:
Shriners Hospitals for Children, 2211 N. Oak Park Avenue, Chicago, IL 60707, USA. lzhao@shrinenet.org
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Alveolar Process / abnormalities
Biomechanics
Child
Cleft Palate / pathology*,  physiopathology
Computer Simulation
Elasticity
Facial Asymmetry / pathology*,  physiopathology
Finite Element Analysis*
Humans
Imaging, Three-Dimensional / methods*
Incisor / abnormalities
Infant
Male
Maxilla / abnormalities*,  growth & development
Maxillofacial Development / physiology
Models, Biological
Stress, Mechanical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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