Document Detail

A strategy to use soft data effectively in randomized controlled clinical trials.
MedLine Citation:
PMID:  2925965     Owner:  NLM     Status:  MEDLINE    
Soft data are defined as measures having substantial intrasubject variability due to errors of measurement or to the inconsistency of subjects' responses. Such data are often important measures of response in randomized clinical trials. In this context, we show that using an intensive design and the slope of response on time as the outcome measure (a) maximizes sample retention and (b) decreases within-group variability, thus (c) maximizing the power of test procedures without requiring increased sample sizes.
H C Kraemer; S Thiemann
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of consulting and clinical psychology     Volume:  57     ISSN:  0022-006X     ISO Abbreviation:  J Consult Clin Psychol     Publication Date:  1989 Feb 
Date Detail:
Created Date:  1989-05-10     Completed Date:  1989-05-10     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0136553     Medline TA:  J Consult Clin Psychol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  148-54     Citation Subset:  IM    
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MeSH Terms
Clinical Trials as Topic / methods*
Follow-Up Studies
Mental Disorders / therapy*
Psychotherapy / methods*
Psychotropic Drugs / therapeutic use*
Random Allocation / methods*
Research Design / methods*
Grant Support
Reg. No./Substance:
0/Psychotropic Drugs

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