Document Detail

A stereologic study of postmature placentas fixed by dual perfusion.
MedLine Citation:
PMID:  7856676     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Placental insufficiency has been considered the cause of increased morbidity in infants delivered postmaturely. Former quantitative studies have indicated a decrease in some placental structures just before term. In this study we describe a method of dual perfusion fixation to provide tissue for stereologic examination. Postmature placentas were examined with this method. STUDY DESIGN: Eleven postmature placentas and 14 placentas delivered at term were fixed by dual perfusion. The volume and the surface area of villi, the trophoblast volume, and the volume, surface area, and length of villous capillaries were estimated by stereologic examination. The Mann-Whitney test (p < or = 0.05) was used for statistical analysis. RESULTS: Morphologic features were normal in all placentas. No significant differences were disclosed in the stereologic estimates of placentas delivered at term and postmature placentas. CONCLUSION: No morphologic or significant quantitative changes were found in postmature placentas.
L G Larsen; H V Clausen; B Andersen; N Graem
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  172     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-03-15     Completed Date:  1995-03-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  500-7     Citation Subset:  AIM; IM    
Pathological-Anatomical Institute, Herlev Hospital, Copenhagen, Denmark.
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MeSH Terms
Placenta / anatomy & histology*,  pathology
Pregnancy, Prolonged*
Prospective Studies
Tissue Fixation / instrumentation,  methods*
Comment In:
Am J Obstet Gynecol. 1995 Aug;173(2):669-70   [PMID:  7645653 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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