Document Detail

A stepdown procedure with feedback for identifying inferiority among three treatments.
MedLine Citation:
PMID:  18932129     Owner:  NLM     Status:  MEDLINE    
This paper considers the problem of identifying which treatments are strictly inferior to the best treatment or treatments in a balanced one-way layout with three treatments, which has important applications in screening trials for new product development. A stepdown procedure is constructed that selects a subset of the treatments containing only treatments that are known to be strictly inferior to the best treatment or treatments. This stepdown procedure uses feedback from the first stage to the second stage that improves its operating characteristics. The advantages accruing from this feedback are demonstrated.
Chen-Ju Lin; A J Hayter
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Biometrical journal. Biometrische Zeitschrift     Volume:  50     ISSN:  1521-4036     ISO Abbreviation:  Biom J     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-10-27     Completed Date:  2008-12-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708048     Medline TA:  Biom J     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  884-96     Citation Subset:  IM    
Department of Industrial Engineering and Management, Yuan Ze University, No. 135 Yuan-Tung Road, Chungli, Taoyuan, Taiwan, R.O.C.
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MeSH Terms
Biometry / methods*
Clinical Trials as Topic / statistics & numerical data*
Confidence Intervals
Models, Statistical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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