| On stent-graft models in thoracic aortic endovascular repair: a computational investigation of the hemodynamic factors. | |
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MedLine Citation:
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PMID: 18342843 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In treating thoracic aortic diseases, endovascular repair involves the placement of a self-expanding stent-graft system across the diseased thoracic aorta. Computational fluid dynamic techniques are applied to model the blood flow by numerically solving the three-dimensional continuity equation and the time-dependent Navier-Stokes equations for an incompressible fluid. From our results, high blood pressure level and high systolic slope of the pressure waveform will significantly increase the drag force on a stent-graft whereas high blood viscosity causes only a mild increase. It indicates that hemodynamic factors might have an important impact on the drag force and thus play a significant role in the risk of stent-graft failure. |
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Authors:
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George S K Fung; S K Lam; Stephen W K Cheng; K W Chow |
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Publication Detail:
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Type: Journal Article Date: 2008-03-14 |
Journal Detail:
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Title: Computers in biology and medicine Volume: 38 ISSN: 0010-4825 ISO Abbreviation: Comput. Biol. Med. Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-03-31 Completed Date: 2008-09-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1250250 Medline TA: Comput Biol Med Country: United States |
Other Details:
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Languages: eng Pagination: 484-9 Citation Subset: IM |
Affiliation:
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Department of Electrical and Electronic Engineering, University of Hong Kong, Pokfulam Road, Hong Kong. skfung@eee.hku.hk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty
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instrumentation* Aorta, Thoracic / physiopathology, surgery Aortic Aneurysm, Thoracic / physiopathology, surgery* Blood Flow Velocity / physiology Blood Pressure / physiology Blood Vessel Prosthesis Implantation* Blood Viscosity / physiology Computer Simulation Equipment Failure Analysis Hemodynamics / physiology* Humans Mathematical Computing* Shear Strength Stents* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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