Document Detail

The status of appendiceal CT in an urban medical center 5 years after its introduction: experience with 753 patients.
MedLine Citation:
PMID:  15908534     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Appendiceal CT was introduced at our hospital in 1996 and now is used in most patients. The use of appendiceal CT has generated controversy and mixed results in various investigations. Our purpose was to determine the percentage of patients for whom CT was performed, incidence of appendicitis, accuracy of CT, percentage of equivocal interpretations, and negative appendectomy rates for those patients who did and did not undergo CT. MATERIALS AND METHODS: Patient records from 2001 that included clinical or CT preoperative examination were analyzed, with follow-up through 2003. Patient age and sex, clinical presentation, CT techniques, CT interpretations, operative reports, pathology reports, and patient disposition were determined. Final diagnoses were provided by pathologic criteria, patient follow-up, or patient survey. Statistical analysis included Fisher's exact test and receiver operating characteristic (ROC) curves. RESULTS: Of 753 patients, 663 (88%) were examined on CT for suspected appendicitis and 90 had an appendectomy without undergoing CT. The incidence of appendicitis in the patients who underwent CT was 39.2%. The sensitivity and specificity of CT were 99% and 95%, respectively; the area under the ROC curve was 0.9896; and the percentage of equivocal CT interpretations was 3.3%. The false-negative appendectomy rates were 3.0% and 5.6% for patients with and without CT, respectively (for all patients, p = 0.326; for female pediatric patients, p = 0.030). CONCLUSION: Five years ago, the negative appendectomy rate dropped from 20% to 7%, and it is now 3.0%. The incidence of appendicitis in patients who are examined on CT is stable compared with similar cohorts from prior investigations. Patients who do not undergo CT also have a low negative appendectomy rate, but this relatively small group is selected on the basis of a convincing clinical presentation. Female pediatric patients likely would have a lower negative appendectomy rate with greater use of CT.
James T Rhea; Elkan F Halpern; Thomas Ptak; James N Lawrason; Richard Sacknoff; Robert A Novelline
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  184     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-05-23     Completed Date:  2005-07-11     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1802-8     Citation Subset:  AIM; IM    
Harvard Medical School and Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.
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MeSH Terms
Acute Disease
Appendicitis / epidemiology,  radiography*,  surgery
Appendix / radiography*
Databases, Factual / statistics & numerical data
False Negative Reactions
False Positive Reactions
Middle Aged
Predictive Value of Tests
ROC Curve
Retrospective Studies
Sensitivity and Specificity
Tomography, X-Ray Computed*
Comment In:
AJR Am J Roentgenol. 2006 Jun;186(6):E23   [PMID:  16714632 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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