Document Detail

A statistical model to predict nonsurvival in congenital diaphragmatic hernia.
MedLine Citation:
PMID:  12032786     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To develop a predictive model using echocardiographic indices to identify nonsurvivors from survivors in preoperative patients with congenital diaphragmatic hernia (CDH). STUDY DESIGN: Eight cases of CDH, with a mortality rate of 38%, underwent echocardiographic study before surgical repair. Left ventricular mass (LVMASS) using the area-length method of Wyatt et al. and fractional shortening (FS) by M-mode measurements were determined. RESULTS: We identified a nonlinear nonoverlapping distribution that predicted nonsurvivors from survivors, p=0.04. Multiple regression analysis demonstrated the quantity (LVMASS x FS)(1/2) to be correlated with nonsurvival with a coefficient of determination r(2)=0.55. Comparison of the means of the quantity (LVMASS x FS)(1/2) for the two groups suggested two distinct populations, p=0.04. CONCLUSION: The mathematical quantity (LVMASS x FS)(1/2) calculated from echocardiographic measurements obtained preoperatively in babies with CDH may predict nonsurvival despite maximal intervention.
Shelley Cypher Springer; Dawn Fleming; Thomas C Hulsey
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  22     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-05-28     Completed Date:  2002-07-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  263-7     Citation Subset:  IM    
Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
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MeSH Terms
Hernia, Diaphragmatic / congenital*,  mortality*,  ultrasonography
Infant, Newborn
Models, Statistical*
Predictive Value of Tests
Comment In:
J Perinatol. 2002 Dec;22(8):682-3; author reply 684   [PMID:  12478457 ]

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