Document Detail

A standardised protocol for the validation of banking methodologies for arterial allografts.
MedLine Citation:
PMID:  23143524     Owner:  NLM     Status:  Publisher    
The objective of this study was to design and test a protocol for the validation of banking methodologies for arterial allografts. A series of in vitro biomechanical and biological assessments were derived, and applied to paired fresh and banked femoral arteries. The ultimate tensile stress and strain, suture pullout stress and strain, expansion/rupture under hydrostatic pressure, histological structure and biocompatibility properties of disinfected and cryopreserved femoral arteries were compared to those of fresh controls. No significant differences were detected in any of the test criteria. This validation protocol provides an effective means of testing and validating banking protocols for arterial allografts.
R J Lomas; P D F Dodd; P Rooney; D E Pegg; P A Hogg; M E Eagle; K E Bennett; A Clarkson; J N Kearney
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-10
Journal Detail:
Title:  Cell and tissue banking     Volume:  -     ISSN:  1573-6814     ISO Abbreviation:  Cell Tissue Bank     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100965121     Medline TA:  Cell Tissue Bank     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
National Health Service Blood and Transplant Tissue Services, Liverpool Centre, 14 Estuary Banks, Speke, Liverpool, L24 8RB, UK,
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