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A standardised breakfast tolerance test in pregnancy: comparison with the 75 g oral glucose tolerance test in unselected mothers and in those with impaired glucose tolerance.
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MedLine Citation:
PMID:  9185485     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is still disagreement concerning the optimal procedure for the diagnosis of milder degrees of hyperglycaemia in pregnancy. We have compared the results of a 75 g oral glucose tolerance test (OGTT) and a standardised breakfast test performed one week apart in 102 non-diabetic women with a singleton pregnancy. There was poor correlation between the two tests (r = 0.15) at two hours, and neither test was predictive of adverse maternal or fetal outcome. One hundred and four patients with impaired glucose tolerance, diagnosed at 30 weeks' gestation by 75 g OGTT, subsequently had a breakfast and lunch meal profile. There was no significant correlation between the two-hour OGTT value and either the two hour post-breakfast value (r = 0.35) or the maximum profile value (r = 0.33). Using the WHO diagnostic criterion of > 8 mmol/l for the OGTT and a maximum glucose concentration > 6.8 mmol/l for the meal profile, there was no relationship between an abnormal result in either test and pregnancy outcome. In our obstetric environment, the 75 g OGTT, a standardised breakfast test, and a structured meal profile, all failed to provide a useful indication of pregnancy outcome in mothers not already known to have diabetes.
Authors:
R N Roberts; J McManus; S Dobbs; D R Hadden
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Ulster medical journal     Volume:  66     ISSN:  0041-6193     ISO Abbreviation:  Ulster Med J     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-07-31     Completed Date:  1997-07-31     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0417367     Medline TA:  Ulster Med J     Country:  NORTHERN IRELAND    
Other Details:
Languages:  eng     Pagination:  18-23     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology, Queen's University of Belfast, Northern Ireland.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Dietary Carbohydrates / administration & dosage
Female
Food*
Glucose Intolerance / blood,  diagnosis*
Glucose Tolerance Test*
Humans
Predictive Value of Tests
Pregnancy
Pregnancy Outcome
Pregnancy in Diabetics / blood,  diagnosis*
Chemical
Reg. No./Substance:
0/Dietary Carbohydrates
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): Ulster Med J
Journal ID (pmc): ulstermedj
ISSN: 0041-6193
Publisher: Ulster Medical Society
Article Information
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Print publication date: Month: 5 Year: 1997
Volume: 66 Issue: 1
First Page: 18 Last Page: 23
ID: 2448708
PubMed Id: 9185485

A standardised breakfast tolerance test in pregnancy: comparison with the 75 g oral glucose tolerance test in unselected mothers and in those with impaired glucose tolerance.
R. N. Roberts
J. McManus
S. Dobbs
D. R. Hadden
Department of Obstetrics and Gynaecology, Queen's University of Belfast, Northern Ireland.



Article Categories:
  • Research Article


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