Document Detail

The staging of Hodgkin's disease in children reviewed.
MedLine Citation:
PMID:  1111956     Owner:  NLM     Status:  MEDLINE    
The accurate staging of Hodgkin's disease is of greater importance in children than in adults, because the deleterious effects of extensive radiation therapy and of prolonged multiple-agent chemotherapy are of greater significance in this age group. The physician concerned with Hodgkin's disease in children must separate those aspects of developments in this field which are applicable to the pediatric age group from the relatively large adult experience. Isotope scanning is effective in demonstrating disseminated disease in pediatric patients. Lymphangiograms are useful, but are more difficult to perform and to interpret in children. When laparotomy is performed in children with clinical Stage I, II, or III Hodgkin's disease, stage will be altered (upward or downward) in approximately 40% of children subjected to the procedure. As growth retardation, skeletal deformity, and secondary neoplasia follow radiotherapy in children, the major function of the laparotomy is to delineate the extent of the disease and thus define appropriate limitations of therapy.
D M Hays
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Cancer     Volume:  35     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1975 Mar 
Date Detail:
Created Date:  1975-05-21     Completed Date:  1975-05-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  973-8     Citation Subset:  AIM; IM    
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MeSH Terms
Hodgkin Disease / diagnosis,  pathology*,  radiography
Radionuclide Imaging

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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