Document Detail


In Vivo spreading of tau pathology.
MedLine Citation:
PMID:  22365536     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Recent findings have suggested that tau pathology may spread in the brain by a prion-like mechanism. In this issue of Neuron, de Calignon et al. (2012) recreated an early stage of neurofibrillary tangle pathology to show that tau aggregates initially generated in a circumscribed area spread throughout the brain and lead to neurodegeneration.
Authors:
Claudio Soto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neuron     Volume:  73     ISSN:  1097-4199     ISO Abbreviation:  Neuron     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-02-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8809320     Medline TA:  Neuron     Country:  United States    
Other Details:
Languages:  eng     Pagination:  621-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Department of Neurology, Mitchell Center for Alzheimer's Disease and Related Brain Disorders, University of Texas Houston Medical School, Houston, TX 77030, USA.
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