Document Detail

A sporadic case of paraganglioma undetected by urine metabolite screening.
MedLine Citation:
PMID:  18458953     Owner:  NLM     Status:  MEDLINE    
Phaeochromocytoma is a rare cause of hypertension in children, but important to be recognised, as hypertension can be severe and surgery is often curative. Here, we report on a 7-year-old boy with a phaeochromocytoma, who had normal levels of commonly assayed catecholamine metabolites in the urine. Postoperatively, the patient developed renal vein thrombosis. Appropriate screening tests for phaeochromocytomas, peri-operative management, and the high incidence of an underlying genetic basis, even in sporadic cases, are discussed.
Detlef Bockenhauer; Lesley Rees; Hartmut Neumann; Ying Foo
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-05-06
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  23     ISSN:  0931-041X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-03     Completed Date:  2008-11-18     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1889-91     Citation Subset:  IM    
Department of Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, WC1N 3JH, UK.
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MeSH Terms
Adrenal Gland Neoplasms / diagnosis*,  genetics
Genetic Testing
Homovanillic Acid / urine*
Pheochromocytoma / diagnosis*,  genetics
Vanilmandelic Acid / urine*
Reg. No./Substance:
306-08-1/Homovanillic Acid; 55-10-7/Vanilmandelic Acid

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