Document Detail


The splenic artery stump pressure is affected by arterial anatomy after proximal embolotherapy in blunt splenic injury.
MedLine Citation:
PMID:  23117382     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Proximal splenic artery embolotherapy can be used as an adjunct to nonoperative management of blunt splenic injury (BSI); however, the hemodynamic changes in the distal splenic artery after proximal splenic artery occlusion are unknown.
METHODS: A retrospective review of 48 patients who underwent transient occlusion of the proximal splenic artery with distal splenic artery pressure measurements was performed. Patients were grouped into those with celiac artery stenosis and those with normal celiac anatomy as determined by contrast-enhanced computed tomography.
RESULTS: Celiac stenosis was identified in 12 (25.0%) of the 48 patients. The celiac stenosis and normal anatomy groups were not statistically different in their systolic pressure, diastolic pressure, mean arterial pressure, age, sex, and splenic injury grade. Transient occlusion of the proximal splenic artery resulted in a decreased distal splenic artery systolic pressure, diastolic pressure, and mean arterial pressure and a decreased systolic and mean perfusion gradient in all patients (42.6 ± 20.8 mm Hg, 39.7 ± 17.8 mm Hg, 40.9 ± 18.9 mm Hg, 67.4 ± 14.5%, and 55.4 ± 17.9%, respectively). The distal splenic artery stump pressure values in the celiac stenosis and normal anatomy patients differed significantly (72.7 ± 32.0 mm Hg vs. 36.7 ± 11.2 mm Hg, 66.6 ± 26.5 mm Hg vs. 34.4 ± 9.3 mm Hg, 69.0 ± 27.9 mm Hg vs. 35.5 ± 10.2 mm Hg, 46.1 ± 19.7% vs. 71.6 ± 8.9%, 28.8 ± 21.6% vs. 60.6 ± 11.7%, for systolic pressure, diastolic pressure, mean arterial pressure, systolic gradient, and mean gradient in celiac stenosis and normal anatomy BSI patients, respectively; all values of p < 0.0001).
CONCLUSION: In hemodynamically stable BSI patients, the systolic pressure in the distal splenic artery is decreased by an average of 67% after proximal splenic artery embolotherapy; however, the pressure reduction in those patients with celiac stenosis is significantly less. This finding may explain some postembolotherapy delayed splenic hemorrhage events.
LEVEL OF EVIDENCE: Prognostic/epidemiologic study, level III; therapeutic study, level IV.
Authors:
Jay Anthony Requarth; Preston R Miller
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of trauma and acute care surgery     Volume:  73     ISSN:  2163-0763     ISO Abbreviation:  J Trauma Acute Care Surg     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-02     Completed Date:  2013-02-11     Revised Date:  2013-09-25    
Medline Journal Info:
Nlm Unique ID:  101570622     Medline TA:  J Trauma Acute Care Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1221-4     Citation Subset:  AIM; IM    
Affiliation:
Wake Forest University Baptist Medical Center, Medical Center Boulevard, Winston-Salem, North Carolina 27106, USA. requarth@wakehealth.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Arterial Pressure / physiology
Celiac Artery / pathology*
Collateral Circulation / physiology
Constriction, Pathologic / complications,  pathology,  physiopathology
Embolization, Therapeutic*
Female
Humans
Male
Middle Aged
Retrospective Studies
Spleen / injuries*
Splenic Artery / physiopathology*
Trauma Centers
Wounds, Nonpenetrating / pathology*,  physiopathology*,  therapy
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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